27 research outputs found

    Implementation of Driver Software of Trailer Module Chip

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    The aim of the project is to develop a driver software for UJA1076A SBC in embedded C using IAR Embedded Workbench and integrate the driver software with application software of Trailer module. Currently MC33903 system basis chip from Freescale is used in Trailer Module. As an initiative to reduce the material cost for the Trailer module product, a lower price SBC NXP UJA1076A has been used. Also due to the fact that the newly proposed SBC has less number of operating modes and registers to configure, it helps in making the driver software much more simpler, thus reducing the risk of hidden issues in the otherwise complex design and code of the current SBC driver software

    Implementation of ERP in an Automobile Manufacturing Shop Floor

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    The implementation of enterprise resource planning (ERP) systems has been known to be much more difficult than the development of a computer application supporting a single business function. This paper addresses the implementation of an ERP system in an automobile manufacture shop floor. This paper examines step by step procedure for implementing an ERP system within the shop floor and also looks improve business process and operations through good business communication system. The Development of a planning module by visual basic programming language were also discussed

    Experimental Study on Behaviour of Clutch Plate Lining using Jute Fibre

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    Clutch plates are usually made of cast iron and high carbon steels. The cast iron has high compressive strength, low tensile strength and low ductility. Clutch lining material is made up of asbestos. In order to obtain good life and more effectiveness and to reduce the cost of clutch plate, the new fibre reinforcement with clutch material is introduced. For the reinforcement with clutch liner material, jute fibre is selected. Due to the reinforcement of the clutch material, the properties has been improved. Then, the comparison of the properties and effectiveness of the new plate with the existing plate is to be done

    Cellular immune response to Mycobacterium tuberculosis-speciWc antigen culture Wltrate protein-10 in south India

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    The Mycobacterium tuberculosis (M. tuberculosis)- speciWc culture Wltrate protein-10 (CFP-10) is highly recognized by M. tuberculosis infected subjects. In the present study, the proliferative response and IFN-� secretion was found for C-terminal peptides of the protein (Cfp651–70, Cfp761–80, Cfp871–90, and Cfp981–100). The alleles HLA DRB1 *04 and HLA DRB1 *10 recognized the C-terminal peptides Cfp7, Cfp8, and Cfp9 in HHC. Cfp6 was predominantly recognized by the alleles HLA DRB1 *03 and HLA DRB1 *15 by PTB. The minimal nonameric epitopes from the C-terminal region were CFP-1056–64 and CFP-1076–84. These two peptides deserve attention for inclusion in a vaccine against tuberculosis in this region

    Immune response to Mycobacterium tuberculosis specific antigen ESAT-6 among south Indians

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    The 6-kDa early secreted antigenic target (ESAT-6) is a T-cell antigen recognized by individuals infected with Mycobacterium tuberculosis. The aim of the study was to identify ‘‘protective epitopes’’ of ESAT-6 protein in the south Indian population. Proliferative and Interferon gamma (IFN-g) responses to ESAT-6 peptides were studied by flow cytometry and Enzyme linked immunosorbent assay (ELISA). Healthy household contacts (HHC) recognized Esp1 (10/17) and Esp6 (9/17) peptides. Among pulmonary tuberculosis patients (PTB), Esp1 (3/11) and Esp6 (5/11) were recognized. Maximal response (7/10) was found for Esp1 and Esp8 in treated patients (TR). Median values for the responding subjects gave the following results: Esp1 (76 pg/ml), Esp6 (64 pg/ml), induced IFN-g production in HHC; PTB gave low IFN-g responses for the peptides. TR responded to the peptides Esp1 (141 pg/ml), Esp8 (102 pg/ml). The proliferation of CD4 cells was similar in both PTB and TR for all peptides; but HHC showed an increase for Esp1 (p < 0.05) and Esp6 (p < 0.01). Esp1 (amino acids aa 1–20) and Esp6 (aa 51–70) were the immunogenic peptides recognized by the alleles HLA DRB1*04 and HLA DRB1*10 among HHC. But the association of the alleles with ESAT-6 peptide presentation needs to be confirmed in a large cohort of subjects. We speculate that ESAT-6 can be used along with other immune-eliciting proteins for vaccine design strategies in south Indian population

    Human protein reference database—2006 update

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    Human Protein Reference Database (HPRD) () was developed to serve as a comprehensive collection of protein features, post-translational modifications (PTMs) and protein–protein interactions. Since the original report, this database has increased to >20 000 proteins entries and has become the largest database for literature-derived protein–protein interactions (>30 000) and PTMs (>8000) for human proteins. We have also introduced several new features in HPRD including: (i) protein isoforms, (ii) enhanced search options, (iii) linking of pathway annotations and (iv) integration of a novel browser, GenProt Viewer (), developed by us that allows integration of genomic and proteomic information. With the continued support and active participation by the biomedical community, we expect HPRD to become a unique source of curated information for the human proteome and spur biomedical discoveries based on integration of genomic, transcriptomic and proteomic data

    Analysis of Electric Motor Magnetic Core Loss under Axial Mechanical Stress

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    The electrical machine core is subjected to mechanical stresses during manufacturing processes. These stresses include radial, circumferential and axial components that may have significant influence on the magnetic properties and it further leads to increase in iron loss and permeability in the stator core. In this research work, analysis of magnetic core iron loss under axial mechanical stress is investigated. The magnetic core is designed with Magnetic Flux Density (MF) ranging from 1.0 T to 1.5 T with estimated dimensions under various input voltages from 5 V to 85 V. Iron losses are predicted by the axial pressure created manually wherever required and is further applied to the designed magnetic core in the range of 5 MPa to 50 MPa. Finite element analysis is employed to estimate the magnetic core parameters and the magnetic core dimensions. A ring core is designed with the selected dimensions for the experimental evaluation. The analysis of iron loss at 50 Hz frequency for non-oriented electrical steel of M400-50A is tested experimentally using the Epstein frame test and force-fit setup test. Experimental evaluation concludes that the magnetic core saturates when it reaches its knee point of the B-H curve of the chosen material and also reveals that the axial pressure has a high impact on the magnetic properties of the material

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    Not AvailableIn order to understand the pathogen’s genetic diversity and dynamics of fungal populations, 34 rice blast isolates collected from various blast endemic areas of India were analyzed using Magnaporthe grisea genome specific microsatellite markers (MGM) and repeat element based Pot2 primer. All the blast isolates showed average pair wise similarities in the range of 0.15 to 0.9 and suggested the large variations with in the isolates collected from the different places. To know the genetic relationship among the blast isolates, a dendogram was generated based on analysis of MGM and Pot2 primers separately and in combination using SHAN/ UPGMA program. The cluster analysis grouped all the blast isolates in to different clusters mostly based on the location, from where they were collected. Based on International blast differential lines containing single resistance genes, it was identified that AVR Pi-k gene was present predominantly in isolate collected from Nellore in costal Andhra Pradesh; and AVR Pi-2 and AVR Pi-4 genes in isolates collected from Mandya (Karnataka). The isolates collected from Almora, Ranchi and Nawagam showed the presence of AVR Pi-1 and AVR Pi-4a genes. The present study helped us to understand the population diversity and their AVR genes spectra in the blast hotspot regions of India, which can be useful in deployment strategies for blast resistance genes in rice improvement programmes.Not Availabl

    Recombinant Newcastle Disease Virus (NDV) Expressing Sigma C Protein of Avian Reovirus (ARV) Protects against Both ARV and NDV in Chickens

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    Newcastle disease (ND) and avian reovirus (ARV) infections are a serious threat to the poultry industry, which causes heavy economic losses. The mesogenic NDV strain R2B is commonly used as a booster vaccine in many Asian countries to control the disease. In this seminal work, a recombinant NDV strain R2B expressing the sigma C (&sigma;C) gene of ARV (rNDV-R2B-&sigma;C) was generated by reverse genetics, characterized in vitro and tested as a bivalent vaccine candidate in chickens. The recombinant rNDV-R2B-&sigma;C virus was attenuated as compared to the parent rNDV-R2B virus as revealed by standard pathogenicity assays. The generated vaccine candidate, rNDV-R2B-&sigma;C, could induce both humoral and cell mediated immune responses in birds and gave complete protection against virulent NDV and ARV challenges. Post-challenge virus shedding analysis revealed a drastic reduction in NDV shed, as compared to unvaccinated birds
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